Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study

Abstract Introduction We evaluated the anti-interleukin-36 receptor antibody spesolimab in patients with moderate-to-severe palmoplantar pustulosis (PPP). Methods This phase IIb trial comprised a loading dose period to week (W) 4, then maintenance dosing to W52. Patients were randomised 2:1:1:1:2 to...

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Detaylı Bibliyografya

Asıl Yazarlar:	A. David Burden, Robert Bissonnette, Alexander A. Navarini, Masamoto Murakami, Akimichi Morita, Thomas Haeufel, Binqi Ye, Frank Baehner, Tadashi Terui
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Adis, Springer Healthcare 2023-09-01
Seri Bilgileri:	Dermatology and Therapy
Konular:	Adverse effects Dose-finding Palmoplantar psoriasis Palmoplantar pustular psoriasis Palmoplantar pustulosis Proof-of-concept
Online Erişim:	https://doi.org/10.1007/s13555-023-01002-1
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