Mechanism of anion exchange and small-molecule inhibition of pendrin
Abstract Pendrin (SLC26A4) is an anion exchanger that mediates bicarbonate (HCO3 −) exchange for chloride (Cl−) and is crucial for maintaining pH and salt homeostasis in the kidney, lung, and cochlea. Pendrin also exports iodide (I−) in the thyroid gland. Pendrin mutations in humans lead to Pendred...
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| Váldodahkkit: | , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Nature Portfolio
2024-01-01
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| Ráidu: | Nature Communications |
| Liŋkkat: | https://doi.org/10.1038/s41467-023-44612-1 |
| Fáddágilkorat: |
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