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Genomic Copy Number Variants in CML Patients With the Philadelphia Chromosome (Ph+): An Update

BackgroundSubmicroscopic segmental imbalances detected by array-comparative genomic hybridization (array-CGH) were discovered to be common in chronic myeloid leukemia (CML) patients with t(9;22) as the sole chromosomal anomaly. To confirm the findings of the previous study and expand the investigati...

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Autori principali: Heyang Zhang, Meng Liu, Xiaoxue Wang, Yuan Ren, Young Mi Kim, Xianfu Wang, Xianglan Lu, Hui Pang, Guangming Liu, Yue Gu, Mingran Sun, Yunpeng Shi, Chuan Zhang, Yaowen Zhang, Jianqin Zhang, Shibo Li, Lijun Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-08-01
Serie:Frontiers in Genetics
Soggetti:
chronic myeloid leukemia
copy number variations
del(9q)
ASS1 gene
additional chromosomal aberrations
Accesso online:https://www.frontiersin.org/articles/10.3389/fgene.2021.697009/full
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