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Anti-CGRP receptor antibodies do not modulate trigeminal pain processing: indication for distinct mechanisms of CGRP pathway blockade

Abstract Background Monoclonal antibodies (mAbs) targeting calcitonin gene-related peptides (CGRP) are established therapies for migraine. There are currently four CGRP-mAbs available on the market: one targets the CGRP receptor, and the other three target the CGRP ligand. Despite the initial compar...

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Hlavní autoři: Kuan-Po Peng, Hauke Basedau, Karl Messlinger, Arne May
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2026-03-01
Edice:The Journal of Headache and Pain
Témata:
QST
Sensitivity
Sensitization
Trigeminal
Preventive
Efficacy
On-line přístup:https://doi.org/10.1186/s10194-026-02316-z
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