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CD70 and PD‐L1 (CD274) co‐expression predicts poor clinical outcomes in patients with pleural mesothelioma

Abstract Diffuse pleural mesothelioma (PM) is a highly aggressive tumour typically associated with short survival. Recently, the effectiveness of first‐line immune checkpoint inhibitors in patients with unresectable PM was reported. CD70–CD27 signalling plays a co‐stimulatory role in promoting T cel...

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Principais autores: Shingo Inaguma, Akane Ueki, Jerzy Lasota, Masayuki Komura, Asraful Nahar Sheema, Piotr Czapiewski, Renata Langfort, Janusz Rys, Joanna Szpor, Piotr Waloszczyk, Krzysztof Okoń, Wojciech Biernat, David S Schrump, Raffit Hassan, Markku Miettinen, Satoru Takahashi
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2023-05-01
Serier:The Journal of Pathology: Clinical Research
Fag:
pleural mesothelioma
immunohistochemistry
CD70
PD‐L1 (CD274)
migration
invasion
Online adgang:https://doi.org/10.1002/cjp2.310
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