High expression of CD38 and MHC class II on CD8+ T cells during severe influenza disease reflects bystander activation and trogocytosis

Abstract Objectives Although co‐expression of CD38 and HLA‐DR reflects T‐cell activation during viral infections, high and prolonged CD38+HLA‐DR+ expression is associated with severe disease. To date, the mechanism underpinning expression of CD38+HLA‐DR+ is poorly understood. Methods We used mouse m...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Xiaoxiao Jia, Brendon Y Chua, Liyen Loh, Marios Koutsakos, Lukasz Kedzierski, Moshe Olshansky, William R Heath, So Young Chang, Jianqing Xu, Zhongfang Wang, Katherine Kedzierska
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2021-01-01
Цуврал:	Clinical & Translational Immunology
Нөхцлүүд:	CD8+ T cell influenza A virus MHC‐II trogocytosis
Онлайн хандалт:	https://doi.org/10.1002/cti2.1336
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!