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Histones present on the surface of late apoptotic cells induce RAGE-mediated phagocytosis

Abstract The receptor for advanced glycation end products (RAGE) is a multiligand receptor that can induce phagocytosis in both professional and nonprofessional phagocytes. We found that histones are another ligand for RAGE and that binding between histones and RAGE is increased when DNA is attached...

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Bibliografiske detaljer
Principais autores: Yuqing Li, Xiaoman Zhou, Yan Yang, Congcong Du, Yi-shi Liu, Zijie Li, Linpei Zhang, Hideki Nakanishi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:Cell Communication and Signaling
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Online adgang:https://doi.org/10.1186/s12964-025-02483-7
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