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Mechanisms of Piperacillin/Tazobactam Nephrotoxicity: Piperacillin/Tazobactam-Induced Direct Tubular Damage in Mice

Piperacillin/tazobactam (PT) is one of the most commonly prescribed antibiotics for critically ill patients in intensive care. PT has been reported to cause direct nephrotoxicity; however, the underlying mechanisms remain unknown. We investigated the mechanisms underlying PT nephrotoxicity using a m...

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Principais autores: Jihyun Yang, Yoon Sook Ko, Hee Young Lee, Yina Fang, Se Won Oh, Myung-Gyu Kim, Won Yong Cho, Sang-Kyung Jo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-06-01
coleção:Antibiotics
Assuntos:
nephrotoxicity
piperacillin/tazobactam
mitochondria
Acesso em linha:https://www.mdpi.com/2079-6382/12/7/1121
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