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Structural and functional insights of sortases and their interactions with antivirulence compounds

Sortase proteins play a crucial role as integral membrane proteins in anchoring bacterial surface proteins by recognizing them through a Cell-Wall Sorting (CWS) motif and cleaving them at specific sites before initiating pilus assembly. Both sortases and their substrate proteins are major virulence...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sowmiya Sri Sivaramalingam, Deepsikha Jothivel, Deenadayalan Karaiyagowder Govindarajan, Lohita Kadirvelu, Muthusaravanan Sivaramakrishnan, Dhivia Dharshika Chithiraiselvan, Kumaravel Kandaswamy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2024-01-01
Saila:Current Research in Structural Biology
Gaiak:
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2665928X24000291
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