Environmental enrichment alleviates neuropathic pain-associated anxiety by enhancing the function of parvalbumin interneurons in the anterior cingulate cortex

Abstract Chronic neuropathic pain is often accompanied with comorbid anxiety. However, effective interventions for this anxiety are highly limited. This study aims to examine the effect of environmental enrichment (EE) on spared nerve injury (SNI)-induced neuropathic pain-associated anxiety behavior...

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Auteurs principaux:	Zhuo-Yu Ren, Bao-Yu Han, Li-Yuan Zhao, Xue-Jie Lou, Yuan-Xiang Tao, Guang-Fen Zhang, Jian-Jun Yang
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2025-03-01
Collection:	Scientific Reports
Sujets:	Environmental enrichment Neuropathic pain PV interneurons Gamma Oscillation
Accès en ligne:	https://doi.org/10.1038/s41598-025-95220-6
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