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Antibody-mediated neutralization of ACBP/DBI has anorexigenic and lipolytic effects

We recently identified acyl coenzyme A-binding protein (ACBP)/diazepam binding inhibitor (DBI) as a novel ‘hunger factor’: a protein that is upregulated in human or murine obesity and that, if administered to mice, causes hyperphagy, adipogenesis and obesity. Conversely, neutralization of ACBP/DBI b...

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Bibliografiske detaljer
Principais autores: Valentina Sica, Isabelle Martins, Omar Motiño, José M. Bravo-San Pedro, Guido Kroemer
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2020-01-01
Serier:Adipocyte
Fag:
Online adgang:http://dx.doi.org/10.1080/21623945.2020.1736734
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