Identification and validation of targets of swertiamarin on idiopathic pulmonary fibrosis through bioinformatics and molecular docking-based approach

Abstract Background Swertiamarin is the main hepatoprotective component of Swertiapatens and has anti-inflammatory and antioxidation effects. Our previous study showed that it was a potent inhibitor of idiopathic pulmonary fibrosis (IPF) and can regulate the expressions of α-smooth muscle actin (α-S...

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Hlavní autoři:	Jun Chang, Shaoqing Zou, Yiwen Xiao, Du Zhu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-10-01
Edice:	BMC Complementary Medicine and Therapies
Témata:	Idiopathic pulmonary fibrosis Traditional Chinese medicine Swertiamarin Bioinformatics Molecular docking
On-line přístup:	https://doi.org/10.1186/s12906-023-04171-w
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