Exploring the potential of the glycerol-3-phosphate dehydrogenase 2 (GPD2) promoter for recombinant gene expression in Saccharomyces cerevisiae

A control point for keeping redox homeostasis in Saccharomyces cerevisiae during fermentative growth is the dynamic regulation of transcription for the glycerol-3-phosphate dehydrogenase 2 (GPD2) gene. In this study, the possibility to steer the activity of the GPD2 promoter was investigated by plac...

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Prif Awduron:	Jan Dines Knudsen, Ted Johanson, Anna Eliasson Lantz, Magnus Carlquist
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2015-09-01
Cyfres:	Biotechnology Reports
Pynciau:	GPD2 promoter Inducible promoter Glycerol-deficient yeast GPD deletion Flow cytometry Redox reporter NADH/NAD+ Population heterogeneity Recombinant protein production
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2215017X15000363
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