Activation of endoplasmic reticulum-mitochondria coupling drives copper-induced autophagy in duck renal tubular epithelial cells

Copper (Cu) as a transition metal can be toxic to public and ecosystem health at high level, but the specific mechanism of Cu-evoked nephrotoxicity remains elusive. Here, we first revealed the crosstalk between mitofusin2 (Mfn2)-dependent mitochondria-associated endoplasmic reticulum membrane (MAM)...

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Detalhes bibliográficos

Principais autores:	Xiaoyu Wang, Huabin Cao, Yukun Fang, He Bai, Jing Chen, Chenghong Xing, Yu Zhuang, Xiaoquan Guo, Guoliang Hu, Fan Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-04-01
coleção:	Ecotoxicology and Environmental Safety
Assuntos:	Copper Mitochondria-associated endoplasmic reticulum membrane (MAM) Autophagy Mitofusin2 Kidney
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0147651322002780
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