PRKCQ-TRIM22 axis promotes proliferation and metastasis of oral squamous cell carcinoma via autophagosome‒lysosome pathway activation

Abstract Background Oral squamous cell carcinoma(OSCC)is the most common oral cancer, featuring aggressive growth and high metastatic potential. Autophagy, the main cellular degradation mechanism, is closely linked to the progression of this cancer, but its specific role and related molecular mechan...

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Библиографические подробности

Главные авторы:	Jinghong Liu, Jianbo Zhang, Qunxiang Chen, Weijia Qing, Yongchun Peng, Zhijing He, Xi Zhou, Huifeng Pi, Bo Li, Qingyun Lin, Junxin Liu, Fan Zhang, Sheng Zhang, Tengfei Fan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-02-01
Серии:	Cancer Cell International
Предметы:	Autophagy PRKCQ Oral squamous cell carcinoma TRIM22 Therapeutic target
Online-ссылка:	https://doi.org/10.1186/s12935-026-04232-3
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