Modeling Stromal Cells Inside the Tumor Microenvironment of Ovarian Cancer: In Vitro Generation of Cancer‐Associated Fibroblast‐Like Cells and Their Impact in a 3D Model

ABSTRACT The tumor microenvironment (TME) is the combination of cells and factors that promotes tumor progression, and cancer‐associated fibroblasts (CAFs) are a key component within TME. CAF originates from various stromal cells and is activated by factors such as transforming growth factor‐beta (T...

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Detalhes bibliográficos

Principais autores:	Jacopo Romoli, Paola Chiodelli, Patrizia Bonassi Signoroni, Elsa Vertua, Clarissa Ferrari, Elisabetta Giuzzi, Alice Paini, Elisa Scalvini, Andrea Papait, Francesca Romana Stefani, Antonietta Rosa Silini, Ornella Parolini
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-05-01
coleção:	MedComm
Assuntos:	3D model cancer‐associated fibroblast ovarian cancer tumor microenvironment
Acesso em linha:	https://doi.org/10.1002/mco2.70172
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