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DNA Methylation Changes in the Postmortem Dorsolateral Prefrontal Cortex of Patients with Schizophrenia

Background: Schizophrenia is a complex psychiatric disorder with a lifetime morbidity rate of 0.5 ―1.0%. The pathophysiology of schizophrenia still remains obscure. Accumulating evidence indicates that DNA methylation, which is the addition of a methyl group to the cytosine in a CpG dinucleotide, mi...

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Principais autores: Numata eShusuke, Tianzhang eYe, Mary eHerman, Barbara eLipska
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014-08-01
叢編:Frontiers in Genetics
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在線閱讀:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00280/full
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