An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells

Abstract The deformability of red blood cells (RBCs) is essential for peripheral circulation and RBC survival and is reportedly altered in several diseases. However, its detail in iron-deficiency (ID) anemia remains poorly understood. We investigated the association between ID and RBC deformability...

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Hlavní autoři:	Kenji Kajitani, Tomohito Ohtani, Rie Higuchi, Misato Chimura, Fusako Sera, Chia-Hung Dylan Tsai, Yasutaka Ueda, Jun-ichi Nishimura, Yasushi Sakata
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-06-01
Edice:	Scientific Reports
Témata:	Deformability Iron deficiency Red blood cell Morphology Ferritin
On-line přístup:	https://doi.org/10.1038/s41598-025-05483-2
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