Antitumor effects of STING agonists on nervous system tumors via tumor-intrinsic STING-STAT1-mediated HMGN2 expression

Objective: Clinical use of stimulator of interferon genes (STING) agonists has challenges due to poor responsiveness and variable efficacy. Therefore, identifying tumor types that are sensitive to these agents and clarifying the underlying mechanisms are essential. Methods: In vitro screening was pe...

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Detalhes bibliográficos

Principais autores:	Zijian Lv, Tiance Wang, Runjia Fan, Qianyi Ming, Jiejie Liu, Yulin Jia, Yan Zhang, Meixia Chen, Wei Chen, Zhengfan Jiang, Weidong Han, Qian Mei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	China Anti-Cancer Association 2026-01-01
Colecção:	Cancer Biology & Medicine
Assuntos:	sting agonists sr-717 tumor immunity hmgn2 biomarker
Acesso em linha:	https://www.cancerbiomed.org/content/23/1/133
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