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Pbx1 and Pbx3 cooperatively regulate intermediate progenitor genesis and corticogenesis in the mouse neocortex

Intermediate progenitor cells (IPCs) are key amplifying neuronal precursors that generate the majority of glutamatergic projection neurons during neocortical development. Despite their central role in corticogenesis, the transcriptional mechanisms controlling IPC proliferation and lineage progressio...

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Principais autores: Asisa Muchamedin, Pauline A. Ulmke, Linh Pham, Hoang Duy Nguyen, Marie-Luise Kümmel, Boris Burr, David Bietz, Petra Wahle, Huu Phuc Nguyen, Tran Tuoc
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
anterior commissure
corpus callosum
cortical development
interhemispheric connectivity
intermediate progenitor cells
layer formation
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2026.1809251/full
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