Insights gained from single-cell analysis of immune cells in tofacitinib treatment of Vogt-Koyanagi-Harada disease

Vogt-Koyanagi-Harada disease (VKH) is an important refractory uveitis mediated by pathological T cells (TCs). Tofacitinib (TOFA) is a JAK- targeted therapy for several autoimmune diseases. However, the specific pathogenesis and targeted therapeutics for VKH remain largely unknown. Based on single-ce...

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Hlavní autoři:	Xiuxing Liu, Qi Jiang, Jianjie Lv, Shizhao Yang, Zhaohao Huang, Runping Duan, Tianyu Tao, Zhaohuai Li, Rong Ju, Yingfeng Zheng, Wenru Su
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical investigation 2022-12-01
Edice:	JCI Insight
Témata:	Autoimmunity Therapeutics
On-line přístup:	https://doi.org/10.1172/jci.insight.162335
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