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Characterisation of the in-vivo miRNA landscape in Drosophila ribonuclease mutants reveals Pacman-mediated regulation of the highly conserved let-7 cluster during apoptotic processes

The control of gene expression is a fundamental process essential for correct development and to maintain homeostasis. Many post-transcriptional mechanisms exist to maintain the correct levels of each RNA transcript within the cell. Controlled and targeted cytoplasmic RNA degradation is one such mec...

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Principais autores: Elisa I. M. Bernard, Benjamin P. Towler, Oliver M. Rogoyski, Sarah F. Newbury
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Genetics
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fgene.2024.1272689/full
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