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Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut

OBJECTIVES:. Determine the role of surfactant protein D (SPD) in sepsis. DESIGN:. Murine in vivo study. SETTING:. Research laboratory at an academic medical center. PATIENTS:. SPD knockout (SPD−/−) and wild-type (SPD+/+) mice. INTERVENTIONS:. SPD−/− and SPD+/+ mice were subjected to cecal ligation a...

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Автори: Jack Varon, MD, MBA, Antonio Arciniegas Rubio, MD, Diana Amador-Munoz, MD, Alexis Corcoran, BA, Joseph A. DeCorte, BS, Colleen Isabelle, BA, Miguel Pinilla Vera, MD, Katherine Walker, MD, MSc, Luke Brown, BSc, Manuela Cernadas, MD, Lynn Bry, MD, PhD, Haopu Yang, Georgios D. Kitsios, MD, PhD, Bryan J. McVerry, MD, Alison Morris, MD, MS, Hyunwook Lee, BA, Judie Howrylak, MD, PhD, Joshua A. Englert, MD, Rebecca M. Baron, MD
Формат: Artigo
Мова:Inglês
Опубліковано: Wolters Kluwer 2022-05-01
Серія:Critical Care Explorations
Онлайн доступ:http://journals.lww.com/10.1097/CCE.0000000000000699
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