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Toxin-antitoxin system gene mutations driving Mycobacterium tuberculosis transmission revealed by whole genome sequencing

BackgroundThe toxin-antitoxin (TA) system plays a vital role in the virulence and pathogenicity of Mycobacterium tuberculosis (M. tuberculosis). However, the regulatory mechanisms and the impact of gene mutations on M. tuberculosis transmission remain poorly understood.ObjectiveTo investigate the in...

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Principais autores: Yawei Hou, Yifan Li, Ningning Tao, Xianglong Kong, Yameng Li, Yao Liu, Huaichen Li, Zhenguo Wang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-07-01
Serier:Frontiers in Microbiology
Fag:
toxin-antitoxin system
Mycobacterium tuberculosis
transmission
whole genome sequencing
single nucleotide polymorphisms
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1398886/full
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