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Comparative evaluation of Biofire Joint Infection Panel, Sepsitest 16S/18S rDNA PCR, and culture to identify microorganisms in explanted heart valves

ABSTRACT Infective endocarditis (IE) is a major life-threatening disease. However, the inability to identify the causative pathogen using conventional microbiological cultures jeopardizes the choice of optimal antibiotic therapy. Culture-independent molecular techniques for pathogen detection may ov...

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Principais autores: Benjamin Berinson, Konstantin Tanida, Manuel Wolters, Flaminia Olearo, Christoph Sinning, Martin Christner, Martin Aepfelbacher, Holger Rohde
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2025-09-01
Series:Microbiology Spectrum
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Acceso en liña:https://journals.asm.org/doi/10.1128/spectrum.01263-25
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