Dibutyl phthalate exposure induces thyroid toxicity through follicular cell pyroptosis via the NRF2/KEAP1/NF-κB pathway

Background Dibutyl phthalate (DBP) is a plasticizer that bioaccumulates in organisms through multiple exposure routes. Although previous studies have documented DBP’s detrimental effects on the reproductive tract, liver, and neurodevelopment, the mechanisms underlying DBP-induced thyrotoxicity are i...

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Principais autores:	Jieyi Wang, Fangda Fu, Yuying Chen, Keqi Fu, Huan Luo, Jiong Yang, Hongfeng Ruan
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis Group 2026-12-01
Series:	Annals of Medicine
Assuntos:	Dibutyl phthalate thyroid gland pyroptosis oxidative stress NRF2-KEAP1 pathway
Acceso en liña:	https://www.tandfonline.com/doi/10.1080/07853890.2026.2643496
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