Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor
Huntington's disease (HD) is a neurodegenerative disease caused by a CAG repeat expansion in the Huntingtin gene (HTT), translated into a Huntingtin protein with a polyglutamine expansion. There is preferential loss of medium spiny neurons within the striatum and cortical pyramidal neurons. Pridopid...
Na minha lista:
| Principais autores: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019-09-01
|
| coleção: | Neurobiology of Disease |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0969996118306120 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|