Cytotoxic T-lymphocyte antigen 4 and programmed cell death ligand 1 blockade increases the effectiveness of interleukin-15 immunotherapy in a bovine leukemia model

Background and Aim: Bovine interleukin 15 (bIL15) is a potential immunotherapy that can block the spread of bovine leukemia virus (BLV). However, immune checkpoints that maintain body homeostasis may reduce their effectiveness. Thus, an analysis of the effectiveness of bIL15 while blocking negative...

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Principais autores:	Kanatbek Mukantayev, Kanat Tursunov, Zhansaya Adish, Darkhan Kanayev, Laura Tokhtarova, Malika Nurtleu, Bisultan Abirbekov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Veterinary World 2024-09-01
coleção:	Veterinary World
Assuntos:	bovine interleukin-15 bovine leukemia virus cytotoxic t-lymphocyte antigen 4 monoclonal antibody programmed cell death ligand 1
Acesso em linha:	https://www.veterinaryworld.org/Vol.17/September-2024/17.pdf
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