Unsaturated fatty acid perturbation combats emerging triazole antifungal resistance in the human fungal pathogen Aspergillus fumigatus

ABSTRACT Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop novel antifungal compounds that are effective against drug-resistant filamentous fungi. Here, we utiliz...

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Dettagli Bibliografici

Autori principali:	Cecilia Gutierrez-Perez, Charles Puerner, Jane T. Jones, Sandeep Vellanki, Elisa M. Vesely, Mark A. Xatse, Andre F. C. Viera, Carissa P. Olsen, Keren O. Attiku, Steven Cardinale, Steven M. Kwasny, Narendran G-Dayanandan, Timothy J. Opperman, Robert A. Cramer
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2024-07-01
Serie:	mBio
Soggetti:	Aspergillus fumigatus antifungal agents sterol regulatory element binding protein fatty acids antifungal resistance
Accesso online:	https://journals.asm.org/doi/10.1128/mbio.01166-24
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