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Non-Competitive Inhibition of Acetylcholinesterase by Bromotyrosine Alkaloids

Fifteen bromotyrosine-derived alkaloids were isolated from the sponge Pseudoceratina cf. purpurea. The acetylcholinesterase-inhibiting activity of all the isolated compounds were examined; to purealidin Q, isoanomoian A, aplyzanzine A, and aplysamine 2 were active with IC 50 values of 1.2, 70, 104,...

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Autors principals: Opeyemi J. Olatunji, Akintayo L. Ogundajo, Ibrahim A. Oladosu, Kanokwan Changwichit, Kornkanok Ingkaninan, Supreeya Yuenyongsawad, Anuchit Plubrukarn
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publishing 2014-11-01
Col·lecció:Natural Product Communications
Accés en línia:https://doi.org/10.1177/1934578X1400901107
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