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Glutaminase inhibition as potential cancer therapeutics: current status and future applications

Alterations in normal metabolic processes are defining features of cancer. Glutamine, an abundant amino acid in the human blood, plays a critical role in regulating several biosynthetic and bioenergetic pathways that support tumour growth. Glutaminolysis is a metabolic pathway that converts glutamin...

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Principais autores: Rajath Cyriac, Kwangho Lee
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 2024-12-01
Serija:Journal of Enzyme Inhibition and Medicinal Chemistry
Teme:
Online dostop:https://www.tandfonline.com/doi/10.1080/14756366.2023.2290911
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