Exploring Autosomal Dominant Non-Syndromic Monogenic Obesity: From Genes to Therapy

Genetic factors are key determinants in the pathophysiology of obesity, regulating energy homeostasis. Monogenic non-syndromic obesity accounts for 2–3% of obesity in both children and adults and is most often attributable to mutations in genes encoding components of the leptin–melanocortin pathway....

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Hlavní autoři:	Giovanni Luppino, Mara Giordano, Francesca Franchina, Roberto Coco, Eleonora Inì, Carla Fazio, Debora Porri, Cecilia Lugarà, Domenico Corica, Tommaso Aversa, Malgorzata Wasniewska
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2026-02-01
Edice:	Current Issues in Molecular Biology
Témata:	<i>MC4R</i> gene <i>SH2B1</i> gene <i>SIM1</i> gene <i>GNAS</i> gene <i>MRAP2</i> gene <i>MC3R</i> gene
On-line přístup:	https://www.mdpi.com/1467-3045/48/2/162
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