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Differential effects of flunixin meglumine and meloxicam on TNF- α production in LPS-stimulated equine neutrophils in vitro

Systemic inflammatory response syndrome (SIRS) induced by endotoxemia is usually secondary to colitis and is a major cause of high morbidity and mortality in horses. Non-steroidal anti-inflammatory drugs (NSAIDs), such as flunixin meglumine (FM) and meloxicam (MX), are used to improve clinical outco...

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Main Authors: Shuntaro Urayama, Ryo Muko, Masanori Muranaka, Hiroshi Mita, Minoru Ohta, Hiroshi Matsuda, Akane Tanaka
Format: Artigo
Language:Inglês
Published: Elsevier 2025-12-01
Series:Veterinary and Animal Science
Subjects:
Endotoxemia
Equine
NSAIDs
TNF-α
Neutrophils
Meloxicam
Online Access:http://www.sciencedirect.com/science/article/pii/S2451943X25000857
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