Inflammatory Effects of Menthol vs. Non-menthol Cigarette Smoke Extract on Human Lung Epithelial Cells: A Double-Hit on TRPM8 by Reactive Oxygen Species and Menthol

Clinical studies suggest that smokers with chronic obstructive pulmonary disease who use menthol cigarettes may display more severe lung inflammation than those who smoke non-menthol cigarette. However, the mechanisms for this difference remain unclear. Menthol is a ligand of transient receptor pote...

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Autori principali:	Tzong-Shyuan Lee, Yu Ru Kou, An-Hsuan Lin, Meng-Han Liu, Hsin-Kuo B. Ko, Diahn-Warng Perng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2017-04-01
Serie:	Frontiers in Physiology
Soggetti:	cigarette smoke menthol TRPM8 reactive oxygen species calcium signaling pathway
Accesso online:	http://journal.frontiersin.org/article/10.3389/fphys.2017.00263/full
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