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Medullary stromal cells define small intestinal lymph node identity in humans and mice

Summary: Lymph nodes (LNs) along the murine gastrointestinal tract are immunologically distinct. Here, we investigate whether such an immune dichotomy globally defines gut LN identity and what drives the regional differences. However, we find that, transcriptionally, it is genes associated with stro...

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Bibliographic Details
Main Authors: Aliia R. Fatkhullina, Johnathan Kent, Hailey Brown, Nathaniel Christiansen, Wioletta Lisicka, Maria Lucia Madariaga, Daria Esterházy
Format: Artigo
Language:Inglês
Published: Elsevier 2025-10-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725012124
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