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DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging

Loss-of-function or knockout mouse models have established a fundamental role for the RNAse III enzyme DICER1 in development and tissue morphogenesis and/or homeostasis. These functions are currently assumed to result mainly from the DICER1-dependent biogenesis of microRNAs which exhibit important g...

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Autores principales: Aurore De Cauwer, Alexandre Mariotte, Jean Sibilia, Seiamak Bahram, Philippe Georgel
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018-07-01
Colección:Frontiers in Immunology
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Acceso en línea:https://www.frontiersin.org/article/10.3389/fimmu.2018.01647/full
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