Elevated levels of colonic interleukin-1beta and interleukin-8 in isolated REM sleep behavior disorder without associated changes in permeability

Abstract Gastrointestinal inflammation could contribute to the early development of Parkinson’s disease (PD). This study investigated gut inflammation, intestinal barrier function, and integrity in patients with isolated REM sleep behavior disorder (iRBD), a prodromal stage of PD. Sigmoid colon biop...

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Hlavní autoři:	Loïc Sellier Montaigne, Simon Lassozé, Adrien de Guilhem de Lataillade, Thibauld Oullier, Marie-Anne Vibet, Kalyane Bach-Ngohou, Malvyne Rolli-Derkinderen, Tony Durand, Séverine Le Dily, Iva Jirka-Alebic, Emmanuel Coron, Quentin Michaux, Michel Neunlist, Giuseppe Madaro, Alessandra Cervino, Pascal Derkinderen, Laurène Leclair-Visonneau
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-04-01
Edice:	npj Parkinson's Disease
On-line přístup:	https://doi.org/10.1038/s41531-026-01340-9
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!