Reversal of neuronal tau pathology via adiponectin receptor activation
Abstract Changes in brain mitochondrial metabolism are coincident with functional decline; however, direct links between the two have not been established. Here, we show that mitochondrial targeting via the adiponectin receptor activator AdipoRon (AR) clears neurofibrillary tangles (NFTs) and rescue...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Portfolio
2025-01-01
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| Schriftenreihe: | Communications Biology |
| Online-Zugang: | https://doi.org/10.1038/s42003-024-07391-z |
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