The emerging double-edged sword role of Sirtuins in the gastric inflammation-carcinoma sequence revealed by bulk and single-cell transcriptomes

Histone modification and the inflammation-carcinoma sequence (ICS) have been acknowledgedly implicated in gastric carcinogenesis. However, the extremum expression of some histone modification genes (HMGs) in intestinal metaplasia (IM) rather than GC obscures the roles of HMGs in ICS. In this study,...

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Principais autores:	Mengyang Wang, Chenxiao Bi, Hong Li, Lizhen Lu, Tao Gao, Panpan Huang, Chengxia Liu, Bin Wang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2022-10-01
סדרה:	Frontiers in Oncology
נושאים:	inflammation-carcinoma sequence gastric cancer histone modification Sirtuins histone deacetylase
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fonc.2022.1004726/full
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