Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation.

In response to peripheral nerve injury, Schwann cells adopt a migratory phenotype and modify the extracellular matrix to make it permissive for cell migration and axonal re-growth. Uridine 5'-triphosphate (UTP) and other nucleotides are released during nerve injury and activate purinergic receptors...

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Библиографические подробности

Главные авторы:	Aloa Lamarca, Alejandro Gella, Tania Martiañez, Mònica Segura, Joana Figueiro-Silva, Carmen Grijota-Martinez, Ramón Trullas, Núria Casals
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2014-01-01
Серии:	PLoS ONE
Online-ссылка:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24905332/pdf/?tool=EBI
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