Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models

ABSTRACT Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription factor signal transducer and activator of transcription 3 (STAT3). To better understand the role of STAT3 during ga...

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Hauptverfasser:	Chad H. Hogan, Shana M. Owens, Glennys V. Reynoso, Yifei Liao, Thomas J. Meyer, Monika A. Zelazowska, Bin Liu, Xiaofan Li, Anna K. Grosskopf, Camille Khairallah, Varvara Kirillov, Nancy C. Reich, Brian S. Sheridan, Kevin M. McBride, Benjamin E. Gewurz, Heather D. Hickman, J. Craig Forrest, Laurie T. Krug
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2024-02-01
Schriftenreihe:	mBio
Schlagworte:	gammaherpesvirus human herpesviruses Kaposi sarcoma-associated herpesvirus latent infection host-pathogen interactions STAT transcription factors
Online-Zugang:	https://journals.asm.org/doi/10.1128/mbio.02998-23
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