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Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments

ABSTRACT George Luedemann is known throughout the antimicrobial community as one of the discoverers of the natural product antibiotic gentamicin. He subsequently hypothesized that slow-growing organisms inhabiting inhospitable, nutrient-limited environments may represent an enriched source of previo...

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Hlavní autoři: Brendan Lin, Sunmin Woo, Alesa Philbrick, John Bacsa, Emily Laskey, Nancy Mehra, Vijay S. Gondil, Jia A. Mei, George Jones, Martin S. Pavelka, Michelle Dziejman, Daniel A. Shutter, Christian Melander, Alexander M. Perritt, Rick Jakober, Yaoyao Shen, Wei-Chen Chang, Cassandra L. Quave, Paul M. Dunman, George Luedemann
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2025-10-01
Edice:mSphere
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On-line přístup:https://journals.asm.org/doi/10.1128/msphere.00367-25
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