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Targeting Orai1-Mediated Store-Operated Ca2+ Entry in Heart Failure

The archetypal store-operated Ca2+ channels (SOCs), Orai1, which are stimulated by the endo/sarcoplasmic reticulum (ER/SR) Ca2+ sensor stromal interaction molecule 1 (STIM1) upon Ca2+ store depletion is traditionally viewed as instrumental for the function of non-excitable cells. In the recent years...

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Hlavní autoři: Rui Luo, Ana-Maria Gomez, Jean-Pierre Benitah, Jessica Sabourin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020-10-01
Edice:Frontiers in Cell and Developmental Biology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fcell.2020.586109/full
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