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Current Insights into Tissue Injury of Giant Cell Arteritis: From Acute Inflammatory Responses towards Inappropriate Tissue Remodeling

Giant cell arteritis (GCA) is an autoimmune disease affecting large vessels in patients over 50 years old. It is an exemplary model of a classic inflammatory disorder with IL-6 playing the leading role. The main comorbidities that may appear acutely or chronically are vascular occlusion leading to b...

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Principais autores: Dimitris Anastasios Palamidas, Loukas Chatzis, Maria Papadaki, Ilias Gissis, Konstantinos Kambas, Evangelos Andreakos, Andreas V. Goules, Athanasios G. Tzioufas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-02-01
coleção:Cells
Assuntos:
giant cell arteritis
pathogenetic mechanism
monocytes
senescence
tissue remodeling
tissue injury
Acesso em linha:https://www.mdpi.com/2073-4409/13/5/430
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