Permeability of the Blood-Brain Barrier and Transport of Nanobodies Across the Blood-Brain Barrier

The presence of a blood-brain barrier (BBB) and a blood-cerebrospinal fluid barrier presents animmense challenge for effective delivery of therapeutics to the central nervous system. Many potential drugs, which are effective at their site of action, have failed due to the lack of distribution in suf...

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Detalhes bibliográficos

Principais autores:	Širochmanová I., Čomor Ľ., Káňová E., Jiménez-Munguía I., Tkáčová Z., Bhide M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Sciendo 2018-03-01
coleção:	Folia Veterinaria
Assuntos:	blood-brain barrier carrier nanobody permeability shuttle transport
Acesso em linha:	https://doi.org/10.2478/fv-2018-0009
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