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Human Induced Pluripotent Stem Cell as a Disease Modeling and Drug Development Platform—A Cardiac Perspective

A comprehensive understanding of the pathophysiology and cellular responses to drugs in human heart disease is limited by species differences between humans and experimental animals. In addition, isolation of human cardiomyocytes (CMs) is complicated because cells obtained by biopsy do not prolifera...

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Principais autores: Mohamed M. Bekhite, P. Christian Schulze
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-12-01
Serier:Cells
Fag:
iPSC
cardiomyocytes
metabolic phenotype
genome-editing
disease modeling
drug testing
Online adgang:https://www.mdpi.com/2073-4409/10/12/3483
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