Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S]

Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of hyperlipidemia and recent genome-wide association studies indicate that genetics plays an important role. Zebrafish are a useful model for studying the genetic susceptibility to hyper...

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Detalles Bibliográficos

Principais autores:	Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2014-11-01
Series:	Journal of Lipid Research
Assuntos:	low density lipoprotein low density lipoprotein receptor atherosclerosis low density lipoprotein cholesterol
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0022227520349774
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