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D-MEKK1, the <it>Drosophila </it>orthologue of mammalian MEKK4/MTK1, and <it>Hemipterous</it>/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

<p>Abstract</p> <p>Background</p> <p>The family of c-Jun NH<sub>2</sub>-terminal kinases (JNK) plays important roles in embryonic development and in cellular responses to stress. Toxic metals and their compounds are potent activators of JNK in mammalian cells. The mechanism of mammalian JNK activati...

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Autors principals: Iordanov Mihail S, Subbian Ezhilkani, Ryabinina Olga P
Format: Artigo
Idioma:Inglês
Publicat: BMC 2006-02-01
Col·lecció:BMC Cell Biology
Accés en línia:http://www.biomedcentral.com/1471-2121/7/7
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