T817MA protects against inflammation and pyroptosis in response to brain ischemia via activating Sirt1 signaling
Abstract Ischemic stroke remains a leading cause of death and disability worldwide, yet effective neuroprotective therapies are lacking. Neuroinflammation and pyroptosis, a lytic and inflammatory form of programmed cell death, exacerbate secondary brain injury post-ischemia. This study investigated...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2025-09-01
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| Series: | Scientific Reports |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1038/s41598-025-18871-5 |
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