Early aperiodic EEG changes in preclinical and prodromal Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is characterized by a gradual buildup of beta amyloid (Aβ) and tau proteins, which disrupt the balance between neuronal excitation and inhibition (E-I), leading to dysfunction in neural network activity. In this study, we examined the aperiodic exponent a...

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Bibliografiske detaljer

Principais autores:	Tjaša Mlinarič, Laure Spruyt, Elvira Khachatryan, Benjamin Wittevrongel, Mariska Reinartz, Koen Van Laere, Patrick Dupont, Rik Vandenberghe, Marc M. Van Hulle
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2026-01-01
Serier:	Alzheimer’s Research & Therapy
Fag:	Sensory stimulation Alzheimer's disease Aperiodic component Excitation-Inhibition balance Electroencephalography PET
Online adgang:	https://doi.org/10.1186/s13195-026-01953-5
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